Microsoft Sculpt Ergonomic Keyboard + Mouse $59.99
This is easily the best price that I've seen for a true ergonomic keyboard and mouse combination (notably on sale at both Best Buy and Amazon.com, although Best Buy dropped the price first.)
Microsoft has put together some pretty good ergonomic computer solutions over the past two years, and all of them have been fairly reasonably priced. If you look for the site in any office supply store such as Staples or Office Depot, you'll find it at a retail list price of $129.99 or above. I'm particularly familiar with this price, because I recently recommended this keyboard set to an organization last month, and they had to purchase it from Office Depot.
Reviews for this set are really high across-the-board, and even without owning one myself, I know from prior experience with Microsoft ergonomic keyboards that your wrists, and your body will thank you if you have to sit in front of computer eight hours a day typing, writing, responding to emails.
Here's a link to Amazon's price (also recently dropped to $60):
It was a one-day 'cyber monday' deal only. Price has been bumped up to $99.99 or $79.99.